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Article

Evidence for balancing of KM, but not GM, alleles by heterotic advantage in South Amerinds.

Human genetics - 1 Aug 1997

Black F L, Pandey J P

Abstract excerpt

Two KM alleles occur in 1075 South Amerinds of 14 tribes in approximately balanced and uniform frequency. However, the number of heterozygotes is 12.7% greater than expected by frequency analysis and 16.5% greater by segregation analysis. This excess is evident in children 0-4 years of age and ma...

Topics

Adolescent
Adult
Alleles
Child
Child, Preschool
Female
Gene Frequency
Haplotypes
Heterozygote
Humans
Immunoglobulin Allotypes
Immunoglobulin Gm Allotypes
Indians, South American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant

Male

Polymorphism, Genetic

Source

Identifiers

PMID: 9254857
DOI: 10.1007/s004390050498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9254857-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Evidence for balancing of KM, but not GM, alleles by heterotic advantage in South Amerinds.PMID 9254857Read ↗

Gm haplotype distribution in Amerindians: relationship with geography and language.Semantic proximity Read ↗

Human genetic diversity (immunoglobulin GM allotypes), linguistic data, and migrations of Amerindian tribes.Semantic proximity Read ↗

Immunoglobulin allotypes (GM and KM) indicate multiple founding populations of Native Americans: evidence of at least four migrations to the New World.Semantic proximity Read ↗

GM and KM allotypes in eight tribal populations of Madyha Pradesh and Orissa, India.Semantic proximity Read ↗

Strong balancing selection at HLA loci: evidence from segregation in South Amerindian families.Semantic proximity Read ↗

[Gm and Km allotypes in a Chilean urban population sample].Semantic proximity Read ↗

Random mating and selection in families against homozygotes for HLA in south Amerindians.Semantic proximity Read ↗

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GM and KM allotypes and GM RFLP allogenotypes in Micronesians from Nauru.Semantic proximity Read ↗

Significant differences in GM allotype frequencies between two sympatric tribes with markedly differential susceptibility to malaria.Semantic proximity Read ↗

Effects of demographic and ethnohistorical factors on average heterozygosities of South Amerindians.Semantic proximity Read ↗

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