Significant differences in GM allotype frequencies between two sympatric tribes with markedly differential susceptibility to malaria.

doi:10.1111/j.1365-3024.2007.00938.x

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Article

Significant differences in GM allotype frequencies between two sympatric tribes with markedly differential susceptibility to malaria.

Parasite immunology - 1 May 2007

Pandey J P, Nasr A, Rocca K M, Troy-Blomberg M, Elghazali G

Abstract excerpt

Fulani and Masaleit, sympatric tribes in eastern Sudan, are characterized by marked differences in susceptibility to Plasmodium falciparum malaria. To determine whether the two tribes differ in the frequency of immunoglobulin GM/KM allotypes, which are associated with immunity to several pathogens, serum samples from 50 Fulani and 50 age- and sex-matched Masaleit subjects were allotyped for several GM/KM...

Topics

Disease Susceptibility
Humans
Immunoglobulin Gm Allotypes
Immunoglobulin Km Allotypes
Linkage Disequilibrium
Malaria
Phenotype

Source

Open in PubMed

Identifiers

PMID: 17430550
DOI: 10.1111/j.1365-3024.2007.00938.x

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