Article
Determination of viral neuraminidase specificity for membrane-bound sialic acids by cell electrophoresis.
Molecular membrane biology - 1 Jan 2000
Gimsa U, Gimsa J
Abstract excerpt
The ability of the influenza virus neuraminidase (NA) to cleave specific sialic acids was measured by cell electrophoresis. Most of the surface charge of human erythrocytes can be attributed to sialic acids. Therefore cleavage of sialic acids reduces the surface charge density which is measurable...
Topics
- Blood
- Electrophoresis
- Erythrocyte Membrane
- Erythrocytes
- Hemagglutinins
- Humans
- Mutation
- Neuraminidase
- Orthomyxoviridae
- Sialic Acids
- Substrate Specificity