Article
Weak N activity of En(a-) human erythrocyte membranes.
American journal of hematology - 1 Nov 1993
Shinozuka T, Miyata Y, Ohyama K, Takei S, Yamakawa T, Kurihara K, Yanagida J
Abstract excerpt
The propositus's erythrocytes with phenotype En(a-), which was found for the first time in a Japanese family, reacted more weakly with anti-N serum than the ordinary phenotype N erythrocytes. The En(a-) erythrocytes lack the major membrane sialoglycoprotein (glycophorin A) as demonstrated by Bio-Gel 1.5m gel filtration from active sialoglycoproteins, which were isolated from En(a-) erythrocyte membranes by the...
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