Article
p53 alterations in thymic epithelial tumours.
Virchows Archiv : an international journal of pathology - 1 Jul 1997
Weirich G, Schneider P, Fellbaum C, Brauch H, Nathrath W, Scholz M, Präuer H, Höfler H
Abstract excerpt
The prognosis of thymic epithelial tumours depends on malignant behaviour that cannot always be predicted on histological grounds. This study aimed at identifying a molecular marker that would be useful in overcoming the drawbacks of histopathology. Forty-four thymic epithelial tumours were analysed for alterations of the tumour suppressor gene p53 using immunohistochemistry (antibodies D0-1 and CM-1) and...
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