Probing the influence of mutations on the stability of a ferredoxin by mass spectrometry.

doi:10.1023/a:1026325914372

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Article

Probing the influence of mutations on the stability of a ferredoxin by mass spectrometry.

Journal of protein chemistry - 1 Jul 1997

Rémigy H, Jaquinod M, Pétillot Y, Gagnon J, Cheng H, Xia B, Markley J L, Hurley J K, Tollin G, Forest E

Abstract excerpt

Hydrogen/deuterium exchange, which depends on solvent accessibility, can be probed by mass spectrometry (MS) to get information on protein conformation or protein-ligand interaction. In this work, the conformational properties of the cyanobacterium Anabaena wild-type ferredoxin as well as of two...

Topics

Bacterial Proteins
Cyanobacteria
Deuterium
Drug Stability
Ferredoxins
Mass Spectrometry
Mutation
Protein Conformation

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