Article
Complete coding regions of two novel HLA-B alleles detected by phototyping (PCR-SSP) in the British caucasoid population: B*5108 and B*5002.
Tissue antigens - 1 Jul 1997
Vilches C, Bunce M, de Pablo R, Murray A K, McIntyre C A, Kreisler M
Abstract excerpt
Two previously reported PCR-SSP variants of the HLA-B locus, B51GAC and B45v, were investigated by RT-PCR cloning and nucleotide sequence analysis of their complete coding regions. They have been shown to correspond to the new alleles B*5108 and B*5002, both of which differ from the common B*5101 and B*5001 subtypes, respectively, by amino acid replacements at their alpha-2 domain alpha-helices. The primary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.