Article
HLA-B*4431: a new HLA-B variant with a complex ancestral history involving HLA-B*44, B*40 and B*07 alleles.
Tissue antigens - 1 Jul 2002
Przemeck M, Elsner H-A, Sel S, Pastucha L T, Blasczyk R
Abstract excerpt
We here describe the identification of the new allele HLA-B*4431, which was found in three members of a Turkish family. Sequencing of the new allele following haplotype-specific PCR amplification revealed that exon 2 is identical to HLA-B*4402, whereas exon 3 resembles a HLA-B*40 variant with the exception of position 572, where a single nucleotide transversion (C > G) leads to an amino acid exchange (Trp162Ser)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
