Article
Luteinizing hormone resistance syndromes.
Annals of the New York Academy of Sciences - 17 Jun 1997
Tsigos C, Latronico C, Chrousos G P
Abstract excerpt
Luteinizing hormone (LH) plays its effects on ovarian and testicular cells through binding to a specific cell surface receptor. We recently described two kindreds with LH resistance due to abnormalities of the LH receptor (LH-R) gene. Affected XY members presented with severe or mild fetal underm...
Topics
- Adolescent
- Adult
- Amenorrhea
- Breast
- Child
- DNA, Complementary
- Female
- Humans
- Luteinizing Hormone
- Male
- Mutation
- Ovary
- Pedigree
- Receptors, LH
- Syndrome
- Testis