Article
Adult T-cell leukemia cells expressing OKT 17 antigen in the activated state.
Hematological oncology - 1 Jan 2000
Tsuda H, Takatsuki K
Abstract excerpt
The surface phenotype and the functional activities of leukemic cells from seven patients with adult T-cell leukemia (ATL) were studied using monoclonal antibodies OKT 3, 4 and 8, anti-Tac, and OKT 17. The latter defines the heterogeneity of the activated T4+ T cell subset. In all cases, ATL cells with the typical OKT3-T4+ T8- phenotype expressed OKT 17 antigen. In addition, in five out of the seven cases the...
Topics
- Adolescent
- Adult
- Aged
- Antibodies, Monoclonal
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- Female
- Humans
- Leukemia
- Lymphocyte Activation
- Male
- Middle Aged