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Article

Revised cytogenetic risk stratification in primary myelofibrosis: analysis based on 1002 informative patients.

Leukemia - 1 May 2018

Tefferi Ayalew, Nicolosi Maura, Mudireddy Mythri, Lasho Terra L, Gangat Naseema, Begna Kebede H, Hanson Curtis A, Ketterling Rhett P, Pardanani Animesh

Abstract excerpt

Current cytogenetic risk stratification in primary myelofibrosis (PMF) is two-tiered: 'favorable' and 'unfavorable'. Recent studies have suggested prognostic heterogeneity within the unfavorable risk category. In 1002 consecutive patients, we performed stepwise analysis of impact on survival from individual and prognostically ordered cytogenetic abnormalities, leading to a revised three-tiered risk model: 'very...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29472717
DOI: 10.1038/s41375-018-0018-z
PMCID: PMC5940654

Genes

ASXL1
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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