Article
Alignment of the genetic and physical maps in the dpy-5 bli-4 (I) region of C. elegans by the serial cosmid rescue of lethal mutations.
Molecular & general genetics : MGG - 1 Jun 1997
McDowall J S, Rose A
Abstract excerpt
Lethal mutations in the 0.5 map unit region between dpy-5 and bli-4 on chromosome I in Caenorhabditis elegans were serially rescued using cosmid-containing transgenic strains. All the lethal mutations analyzed came from a set of 495 EMS-induced, sDp2-rescued lethals described previously. Germline...
Topics
- Animals
- Animals, Genetically Modified
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosome Mapping
- Cosmids
- Crosses, Genetic
- Disorders of Sex Development
- Extrachromosomal Inheritance
- Female
- Forkhead Transcription Factors
- Genes, Helminth
- Genetic Complementation Test
- Male
- Mutation
- Phenotype
- Restriction Mapping
- Transformation, Genetic