Article
Relationship between aflatoxin biosynthesis and sporulation in Aspergillus parasiticus.
Fungal genetics and biology : FG & B - 1 Apr 1997
Guzmán-de-Peña D, Ruiz-Herrera J
Abstract excerpt
Regulation of aflatoxin biosynthesis during differentiation of Aspergillus parasiticus was analyzed by using a drug that inhibits the development of the fungus and mutants affected in sporulation. Diaminobutanone, a competitive inhibitor of ornithine decarboxylase, repressed spore germination. If added after spore germination had occurred, it blocked sporulation completely and suppressed aflatoxin biosynthesis,...
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