Article
Quantitative and spatial information on the composition of chimaeric fetal mouse eyes from single histological sections.
Development, growth & differentiation - 1 Jun 1997
West J D, Hodson B A, Keighren M A
Abstract excerpt
The spatial distribution of cells in chimaeric tissues, composed of two genotypes, provides insights into the extent of cell mixing during development and growth. However, direct measurement of patch sizes is not usually meaningful because, when the proportion of one genotype is high, a single patch may encompass several adjacent coherent clones of like genotype (clone aggregation). Two previously used methods of...
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