Article
Mismatch between myosin heavy chain mRNA and protein distribution in human skeletal muscle fibers.
The American journal of physiology - 1 Jun 1997
Andersen J L, Schiaffino S
Abstract excerpt
The distribution of myosin heavy chain (MHC) isoforms was analyzed at the protein and mRNA levels in human skeletal muscle biopsies from young normal adult subjects. Using ATPase histochemical reactions, antibodies to fast- and slow-type MHCs, and in situ hybridization with probes specific for MHC-beta/slow, MHC-2A, and MHC-2X, we confirmed our previous results showing that most fibers contain either a single...
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