Article
Bed rest increases the amount of mismatched fibers in human skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Feb 1999
Andersen J L, Gruschy-Knudsen T, Sandri C, Larsson L, Schiaffino S
Abstract excerpt
The effects of a 37-day period of bed rest on myosin heavy chain (MHC) expression on both mRNA and protein level in human skeletal muscle fibers were studied. Muscle biopsies from vastus lateralis muscle were obtained from seven healthy young male subjects before and after the bed-rest period. Combined in situ hybridization, immunocytochemistry, and ATPase histochemistry analysis of serial sections of the muscle...
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