Article
H-NS and RpoS regulate emergence of Lac Ara+ mutants of Escherichia coli MCS2.
Journal of bacteriology - 1 Jul 1997
Gómez-Gómez J M, Blázquez J, Baquero F, Martínez J L
Abstract excerpt
Two master growth-phase regulatory proteins, H-NS and sigmaS, are involved in the formation of araB-lacZ fusion clones of Escherichia coli MCS2. The stationary-phase sigma factor RpoS is strictly required for the appearance of such mutants, whereas the histone-like protein H-NS represses their emergence. Our results support the idea that genetic changes leading to adaptive mutation in this model system are...
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