Article
Bacillus subtilis CcdA-defective mutants are blocked in a late step of cytochrome c biogenesis.
Journal of bacteriology - 1 Jul 1997
Schiött T, Throne-Holst M, Hederstedt L
Abstract excerpt
Cytochromes of the c type contain covalently bound heme. In bacteria, they are located on the outside of the cytoplasmic membrane. Cytochrome c synthesis involves export of heme and apocytochrome across the cytoplasmic membrane followed by ligation of heme to the polypeptide. Using radioactive protoheme IX produced in Escherichia coli, we show that Bacillus subtilis can use heme from the growth medium for...
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