Article
Absence of mutations in the gene encoding thyroid transcription factor-1 (TTF-1) in patients with thyroid dysgenesis.
Thyroid : official journal of the American Thyroid Association - 1 Jun 1997
Perna M G, Civitareale D, De Filippis V, Sacco M, Cisternino C, Tassi V
Abstract excerpt
Thyroid transription factor-1 (TTF-1) is a homeodomain-containing nuclear transcription factor, important in regulation of the thyroid-specific genes thyroglobulin (Tg), thyroperoxidase (TPO), and thyrotropin receptor (TSHR). TTF-1 is an early biochemical marker of thyroid differentiation, essent...
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