Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope

doi:10.1128/jvi.71.8.6247-6252.1997

Article

Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope

1 Aug 1997

Abstract excerpt

We have determined that three type-specific and conformationally dependent monoclonal antibodies, H16.E70, H16.U4, and H16.V5, neutralize pseudotype human papillomavirus type 16 (HPV16) virions in vitro. H16.U4 and H16.V5 neutralized pseudotype virions derived from the German HPV16 variant 114K and the Zairian variant Z-1194 with equal efficiency. In contrast, neutralization of Z-1194 pseudotype virions by...

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