Portal vein thrombosis in association with factor V Leiden mutation in a patient with hepatocellular carcinoma.

doi:10.1002/(sici)1096-911x(199709)29:3<224::aid-mpo12>3.0.co;2-d

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Portal vein thrombosis in association with factor V Leiden mutation in a patient with hepatocellular carcinoma.

Medical and pediatric oncology - 1 Sept 1997

Gürgey A, Büyükpamukcu M, Baskut C, Yalcin B, Gögüş S

Abstract excerpt

We report a case of hepatocellular carcinoma associated with portal vein thrombosis. Analysis of whole cellular DNA demonstrated heterozygosity for the factor V Leiden mutation. The patient also had marked protein C deficiency. The presence of the mutation associated with protein C deficiency may increase the risk of thrombosis in this patient with hepatocellular carcinoma.

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Portal vein thrombosis in association with factor V Leiden mutation in a patient with hepatocellular carcinoma.

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