Cw*1701 defines a divergent african HLA-C allelic lineage.

doi:10.1007/s002510050259

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Article

Cw*1701 defines a divergent african HLA-C allelic lineage.

Immunogenetics - 1 Jan 1997

Wells R S, Seielstad M T, Bunce M, Tyan D B, Bekele E, Parham P

Abstract excerpt

The complete sequence of a new HLA-C allele, Cw*1701, was determined from a South African Zulu individual. Unique features that distinguish Cw*1701 from other HLA-C alleles include multiple point substitutions and an 18 nucleotide insertion in exon 5, which encodes the transmembrane domain. In a...

Topics

Africa
Alleles
Base Sequence
Gene Frequency
Genes, MHC Class I
HLA-C Antigens
Haplotypes
Humans
Molecular Sequence Data
Phylogeny
Sequence Alignment
Sequence Homology, Nucleic Acid

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