Article
Cw*1701 defines a divergent african HLA-C allelic lineage.
Immunogenetics - 1 Jan 1997
Wells R S, Seielstad M T, Bunce M, Tyan D B, Bekele E, Parham P
Abstract excerpt
The complete sequence of a new HLA-C allele, Cw*1701, was determined from a South African Zulu individual. Unique features that distinguish Cw*1701 from other HLA-C alleles include multiple point substitutions and an 18 nucleotide insertion in exon 5, which encodes the transmembrane domain. In a phylogenetic analysis of HLA-C sequences, Cw*1701 forms a third, distinct allelic lineage. A comparison of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
