Article
Molecular characterization of a novel, serologically detectable, HLA-C allele: Cw*1602.
Human immunology - 1 Oct 1994
Vilches C, Herrero M J, de Pablo R, Moreno M E, Bunce M, Kreisler M
Abstract excerpt
Cw*1602, a novel HLA-C allele belonging to the newly assigned Cw*16 group, has been cloned and sequenced from a Spanish Caucasoid cell expressing a "Cw6.2" phenotype. Some of the polymorphic substitutions of the new allele, and linkage disequilibrium to B51, had been predicted on the basis of previously published studies. The primary structure of Cw*1602 is in agreement with its serologic reactivity and, in...
Topics
- Alleles
- Amino Acid Sequence
- B-Lymphocytes
- Base Sequence
- Cell Line
- HLA-C Antigens
- Humans
- Molecular Sequence Data
