Purification of bovine lysosomal alpha-mannosidase, characterization of its gene and determination of two mutations that cause alpha-mannosidosis.

doi:10.1111/j.1432-1033.1997.00410.x

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Article

Purification of bovine lysosomal alpha-mannosidase, characterization of its gene and determination of two mutations that cause alpha-mannosidosis.

European journal of biochemistry - 1 Jun 1997

Tollersrud O K, Berg T, Healy P, Evjen G, Ramachandran U, Nilssen O

Abstract excerpt

Bovine kidney lysosomal alpha-mannosidase was purified to homogeneity and the gene was cloned. The gene was organized in 24 exons that spanned 16 kb and its corresponding cDNA contained an open reading frame of 2997 bp beginning from a putative ATG start codon. The deduced amino acid sequence con...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cattle
Chromatography, Gel
Chromatography, Ion Exchange
DNA, Complementary
Electrophoresis, Polyacrylamide Gel
Exons
Mannosidases
Molecular Sequence Data
Mutation
Sequence Homology, Amino Acid
Species Specificity
alpha-Mannosidase
alpha-Mannosidosis

Source

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Identifiers

PMID: 9208932
DOI: 10.1111/j.1432-1033.1997.00410.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9208932-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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