Article
Molecular evolution of cytochrome c oxidase: rate variation among subunit VIa isoforms.
Molecular biology and evolution - 1 Jun 1997
Schmidt T R, Jaradat S A, Goodman M, Lomax M I, Grossman L I
Abstract excerpt
Cytochrome c oxidase (COX) consists of 13 subunits, 3 encoded in the mitochondrial genome and 10 in the nucleus. Little is known of the role of the nuclear-encoded subunits, some of which exhibit tissue-specific isoforms. Subunit VIa is unique in having tissue-specific isoforms in all mammalian species examined. We examined relative evolutionary rates for the COX6A heart (H) and liver (L) isoform genes along the...
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