bcl-2 Expression in Pilomatricoma

doi:10.1097/00000372-199706000-00009

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bcl-2 Expression in Pilomatricoma

1 Jun 1997

Abstract excerpt

Pilomatricoma is a distinctive tumor characterized by a dual population of proliferating basophilic cells and diagnostic shadow cells, believed to arise from the hair matrix. The normal hair matrix undergoes defined cycles of growth (anagen), regression (catagen), and resting (telogen) that are regulated by programmed cell death (apoptosis). bcl-2 is a proto-oncogene that helps to suppress apoptosis in both...

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PMID: 9185911
DOI: 10.1097/00000372-199706000-00009

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