Did the loss of endogenous ascorbate propel the evolution of Anthropoidea and Homo sapiens?

doi:10.1016/s0306-9877(97)90033-5

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Article

Did the loss of endogenous ascorbate propel the evolution of Anthropoidea and Homo sapiens?

Medical hypotheses - 1 May 1997

Challem J J

Abstract excerpt

It has been previously theorized that free-radical reactions led to the first life on Earth, and their ability to randomly cause mutations may have subsequently led to the evolution of life. One of the most efficient free-radical quenchers is ascorbate, which most animals manufacture endogenously...

Topics

Aging
Animals
Ascorbic Acid
Ascorbic Acid Deficiency
Biological Evolution
Free Radicals
Gene Deletion
Haplorhini
Hominidae
Humans
Models, Biological
Mutation

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