Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer.

doi:10.1038/sj.onc.1201054

Article

Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer.

Oncogene - 8 May 1997

Shridhar V, Rivard S, Wang X, Shridhar R, Paisley C, Mullins C, Beirnat L, Dugan M, Sarkar F, Miller O J, Vaitkevicius V K, Smith D I

Abstract excerpt

The ARP gene encodes a highly conserved arginine-rich protein from chromosomal band 3p21.1. At the cytogenetic level this region is frequently deleted in a variety of different solid tumors, although not in pancreatic cancer. We have reported the presence of a specific mutation (ATG50-->AGG) or deletion of codon 50 of the ARP gene in different tumor types (Shridhar et al., 1996, 1996a). In the present study, we...

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