Article
Molecular alterations in pancreatic tumors.
World journal of gastroenterology - 7 Jun 2021
Visani Michela, Acquaviva Giorgia, De Leo Antonio, Sanza Viviana, Merlo Lidia, Maloberti Thais, Brandes Alba A, Franceschi Enrico, Di Battista Monica, Masetti Michele, Jovine Elio, Fiorino Sirio, Pession Annalisa, Tallini Giovanni, de Biase Dario
Abstract excerpt
Genetic alterations in pancreatic tumors can usually be classified in: (1) Mutational activation of oncogenes; (2) Inactivation of tumor suppressor genes; and (3) Inactivation of genome maintenance genes controlling the repair of DNA damage. Endoscopic ultrasound-guided fine-needle aspiration has improved pre-operative diagnosis, but the management of patients with a pancreatic lesion is still challenging....
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