Article
Newborn screening for cystic fibrosis in Wisconsin: comparison of biochemical and molecular methods.
Pediatrics - 1 Jun 1997
Gregg R G, Simantel A, Farrell P M, Koscik R, Kosorok M R, Laxova A, Laessig R, Hoffman G, Hassemer D, Mischler E H, Splaingard M
Abstract excerpt
OBJECTIVES: To evaluate neonatal screening for cystic fibrosis (CF), including study of the screening procedures and characteristics of false-positive infants, over the past 10 years in Wisconsin. An important objective evolving from the original design has been to compare use of a single-tier immunoreactive trypsinogen (IRT) screening method with that of a two-tier method using IRT and analyses of samples for...
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