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Article

A new cystic fibrosis newborn screening algorithm: IRT/IRT1 upward arrow/DNA.

The Journal of pediatrics - 1 Nov 2009

Sontag Marci K, Wright Dan, Beebe James, Accurso Frank J, Sagel Scott D

Abstract excerpt

OBJECTIVE: To evaluate an immunoreactive trypsinogen (IRT) IRT/IRT1 upward arrow/DNA algorithm, aimed at improving sensitivity while decreasing cystic fibrosis (CF) carrier identification. STUDY DESIGN: New technologies allow the measurement of the second IRT level solely in infants with an elevated first IRT level. Specimens with an elevated second IRT level undergo mutation analysis. We tested the projected...

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Source

Identifiers

PMID: 19540513
DOI: 10.1016/j.jpeds.2009.03.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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