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Detection of Treponema pallidum by a sensitive reverse transcriptase PCR

1 Jun 1997

Abstract excerpt

Syphilis is diagnosed by serologic testing or by identification of the causative agent, Treponema pallidum. The bacterium has historically been detected in clinical specimens by dark-field microscopy, immunostaining with polyclonal or monoclonal antibodies, or the rabbit inoculation test (RIT). RIT is considered to be very sensitive and specific, although it is available only in research settings and is not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9163442
DOI: 10.1128/jcm.35.6.1348-1352.1997

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