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The frequency and developmental capability of human embryos containing multinucleated blastomeres

1 Apr 1997

Abstract excerpt

The frequency of multinucleated blastomeres (MNB) in 2- and 4-cell stage human embryos was recorded immediately before embryo transfer using a high-power inverted microscope. About 44% of patients (150/338) possessed embryos exhibiting MNB. The appearance of this nuclear abnormality was not correlated with maternal age. Overall, 15% of the otherwise good quality embryos (274/1885) that developed after monospermic...

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PMID: 9159445
DOI: 10.1093/humrep/12.4.800

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