Article
Animal models of human genetic diseases: do they need to be faithful to be useful?
Molecular genetics and genomics : MGG - 1 Jul 2011
Guénet Jean-Louis
Abstract excerpt
With the advances in molecular genetics, animal models of human diseases are becoming more numerous and more refined every year. Despite this, one must recognize that they generally do not faithfully and comprehensively mimic the homologous human disease. Faced with these imperfections, some geneticists believe that these models are of little value, while for others, on the contrary, they are important tools. We...
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