Article
Comprehensive BRCA mutation analysis in the Greek population. Experience from a single clinical diagnostic center.
Cancer genetics - 1 Jan 2018
Apessos Angela, Agiannitopoulos Konstantinos, Pepe Georgia, Tsaousis Georgios N, Papadopoulou Eirini, Metaxa-Mariatou Vasiliki, Tsirigoti Angeliki, Efstathiadou Chrysoula, Markopoulos Christos, Xepapadakis Grigorios, Venizelos Vasileios, Tsiftsoglou Aris, Natsiopoulos Ioannis, Nasioulas George
Abstract excerpt
Germline mutations in the BRCA1 and BRCA2 genes are associated with hereditary predisposition to breast and ovarian cancer. Sensitive and accurate detection of BRCA1 and BRCA2 mutations is crucial for personalized clinical management of individuals affected by breast or ovarian cancer, and for the identification of at-risk healthy relatives. We performed molecular analysis of the BRCA1 and BRCA2 genes in 898...
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