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Article

A method for determining transmembrane protein structure.

Molecular membrane biology - 1 Jan 2000

Jones P C, Sivaprasadarao A, Wray D, Findlay J B

Abstract excerpt

A simple and rapid protein chemical approach for determining the transmembrane structure of membrane proteins is described. The method involves single substitutions of consecutive amino acid residues, within putative transmembrane segments, to cysteine. This is followed by the analysis of their susceptibility to modification by maleimides with different physico-chemical properties. Fluorescein-5-maleimide (FM),...

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PMID: 9147663
DOI: 10.3109/09687689609160575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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