Article
Transport of vitamin D metabolites.
Clinical orthopaedics and related research - 1 Jan 2000
Haddad J G
Abstract excerpt
Vitamin D and its metabolites are bound to an alpha globulin (DBP) in human serum. This carrier protein binds 25-OHD and 24,25(OH)2D with higher affinity than vitamin D or 1,25(OH)2D, but the binding is highly specific for the vitamin D structure. The carrier mechanism appears to be unique in that it is a high affinity and high capacity system, capable of binding as much as 120,000 IU of biological activity per...
Topics
- Adult
- Alleles
- Alpha-Globulins
- Animals
- Binding Sites
- Biological Transport
- Blood Proteins
- Carrier Proteins
- Child
- Cytosol
- Female
- Gene Frequency
- Humans