Article
Serum free and bio-available 25-hydroxyvitamin D correlate better with bone density than serum total 25-hydroxyvitamin D.
Scandinavian journal of clinical and laboratory investigation - 1 Apr 2014
Johnsen Martin S, Grimnes Guri, Figenschau Yngve, Torjesen Peter A, Almås Bjørg, Jorde Rolf
Abstract excerpt
In the circulation 25-hydroxyvitamin D (25(OH)D) is bound to vitamin D-binding protein (DBP) and albumin. Only a small fraction is in the unbound, free form. According to the 'free-hormone-hypothesis' only the free form is biologically active. Genetic differences in DBP may affect the binding to 25(OH)D and thereby the amount of free 25(OH)D. In the present study sera were obtained from 265 postmenopausal women...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
