Article
The origin and evolution of animal appendages.
Proceedings of the National Academy of Sciences of the United States of America - 13 May 1997
Panganiban G, Irvine S M, Lowe C, Roehl H, Corley L S, Sherbon B, Grenier J K, Fallon J F, Kimble J, Walker M, Wray G A, Swalla B J, Martindale M Q, Carroll S B
Abstract excerpt
Animals have evolved diverse appendages adapted for locomotion, feeding and other functions. The genetics underlying appendage formation are best understood in insects and vertebrates. The expression of the Distal-less (Dll) homeoprotein during arthropod limb outgrowth and of Dll orthologs (Dlx) in fish fin and tetrapod limb buds led us to examine whether expression of this regulatory gene may be a general...
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