Article
Organogenesis in deep time: A problem in genomics, development, and paleontology.
Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2015
Pieretti Joyce, Gehrke Andrew R, Schneider Igor, Adachi Noritaka, Nakamura Tetsuya, Shubin Neil H
Abstract excerpt
The fossil record is a unique repository of information on major morphological transitions. Increasingly, developmental, embryological, and functional genomic approaches have also conspired to reveal evolutionary trajectory of phenotypic shifts. Here, we use the vertebrate appendage to demonstrate how these disciplines can mutually reinforce each other to facilitate the generation and testing of hypotheses of...
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