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Article

Isolation of Aspergillus nidulans mutants that overcome brlA-induced growth arrest.

Fungal genetics and biology : FG & B - 1 Feb 1997

Marhoul J, Adams T H

Abstract excerpt

The Aspergillus nidulans brlA gene is a primary regulator of development-specific gene expression during conidiation. Forced activation of brlA in vegetative cells leads to inappropriate induction of conidiophore formation and causes growth to stop. In fact, when conidia containing a nutritionally inducible brlA gene fusion are placed on inducing medium, they fail to germinate. We used this phenotype to select...

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PMID: 9126620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Isolation of Aspergillus nidulans mutants that overcome brlA-induced growth arrest.PMID 9126620Read ↗

Identification of developmental regulatory genes in Aspergillus nidulans by overexpression.Semantic proximity Read ↗

The Aspergillus nidulans brlA regulatory locus consists of overlapping transcription units that are individually required for conidiophore development.Semantic proximity Read ↗

Genetic requirements for initiating asexual development in Aspergillus nidulans.Semantic proximity Read ↗

Complex control of the developmental regulatory locus brlA in Aspergillus nidulans.Semantic proximity Read ↗

FluG and flbA function interdependently to initiate conidiophore development in Aspergillus nidulans through brlA beta activation.Semantic proximity Read ↗

brlA requires both zinc fingers to induce development.Semantic proximity Read ↗

Dominant mutations affecting both sporulation and sterigmatocystin biosynthesis in Aspergillus nidulans.Semantic proximity Read ↗

Aspergillus fumigatus flbB encodes two basic leucine zipper domain (bZIP) proteins required for proper asexual development and gliotoxin production.Semantic proximity Read ↗

Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatus.Semantic proximity Read ↗

Proteomic analyses reveal the key roles of BrlA and AbaA in biogenesis of gliotoxin in Aspergillus fumigatus.Semantic proximity Read ↗

Extragenic suppressors of loss-of-function mutations in the aspergillus FlbA regulator of G-protein signaling domain protein.Semantic proximity Read ↗

Wild-type and mutant alleles of the Aspergillus nidulans developmental regulator gene brlA: correlation of variant sites with protein function.Semantic proximity Read ↗

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