Article
brlA requires both zinc fingers to induce development.
Molecular and cellular biology - 1 Apr 1990
Adams T H, Deising H, Timberlake W E
Abstract excerpt
Expression of the Aspergillus nidulans brlA gene induces a developmental pathway leading to the production of asexual spores. We have introduced mutations into brlA that are expected to disrupt either or both Cys2-His2 Zn(II) coordination sites postulated to exist in the BrlA polypeptide. The resultant brlA alleles fail to induce either the asexual reproductive pathway or the expression of development-specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.