Article
brlA requires both zinc fingers to induce development.
Molecular and cellular biology - 1 Apr 1990
Adams T H, Deising H, Timberlake W E
Abstract excerpt
Expression of the Aspergillus nidulans brlA gene induces a developmental pathway leading to the production of asexual spores. We have introduced mutations into brlA that are expected to disrupt either or both Cys2-His2 Zn(II) coordination sites postulated to exist in the BrlA polypeptide. The res...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Aspergillus nidulans
- Base Sequence
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Metalloproteins
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Sequence Homology, Nucleic Acid
- Spores, Fungal
- Transcription Factor TFIIIA
- Transcription Factors
- Xenopus laevis
- Zinc