Article
Polymorphism of the h allele and the population frequency of sporadic nonfunctional alleles.
Transfusion - 1 Mar 1997
Wagner F F, Flegel W A
Abstract excerpt
BACKGROUND: Current polymerase chain reaction-based strategies for phenotype prediction often fail when sporadic nonfunctional alleles are encountered. The population frequency of such mutations was not known for any gene under low selection pressure and may be best examined in blood groups systems lacking prevalent nonfunctional alleles. The frequency of the very rare Bombay blood group (Oh, genotype hh sese)...
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