Article
Smoothelin expression characteristics: development of a smooth muscle cell in vitro system and identification of a vascular variant.
Cell structure and function - 1 Feb 1997
van Eys G J, Völler M C, Timmer E D, Wehrens X H, Small J V, Schalken J A, Ramaekers F C, van der Loop F T
Abstract excerpt
Recently we described a protein, smoothelin, that has been exclusively found in smooth muscle cells (SMC). The human cDNA has been cloned from a colon cDNA library and the putative protein sequence was deduced. Smoothelin does not belong to a known protein family but shows a partial homology with members of the spectrin family. Transfection studies revealed that smoothelin has an affinity for actin and is either...
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