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Article

Saporin 6 and lonidamine in primary cell cultures from human breast carcinomas: a synergistic effect.

Anti-cancer drug design - 1 Mar 1997

Gasperi-Campani A, Roncuzzi L, Zoli W, Amadori D

Abstract excerpt

Lonidamine (LND) is a potential chemotherapeutic agent which can positively modulate the efficacy of several antineoplastic agents. The ribosome-inactivating protein Saporin 6 (SO 6), which acts as a rRNA N-glycosidase and a DNA nuclease, has recently attracted interest as a novel potential anticancer and antiviral agent. Synergism between LND and SO 6 was previously demonstrated by us in the human metastatic...

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PMID: 9113064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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