Article
Relation of haemolytic anaemia and erythrocyte-bound IgG in alpha- and beta-thalassaemic syndromes.
European journal of haematology - 1 Feb 1997
Chinprasertsuk S, Wanachiwanawin W, Pattanapanyasat K, Tatsumi N, Piankijagum A
Abstract excerpt
There has been evidence that IgG-mediated phagocytosis plays some part in destruction of erythroid cells and subsequent anaemia in thalassaemia. In this study using direct immunofluorescence and flow cytometry, erythrocyte-bound IgG was studied in 53 and 33 beta-thal/Hb E and Hb H patients, respectively. The mean percentages of IgG-positive erythrocytes in both nonsplenectomized (4.4%) and splenectomized (24%)...
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