Article
Drosophila protein phosphatase V functionally complements a SIT4 mutant in Saccharomyces cerevisiae and its amino-terminal region can confer this complementation to a heterologous phosphatase catalytic domain.
The EMBO journal - 1 Dec 1993
Mann D J, Dombrádi V, Cohen P T
Abstract excerpt
The sequence of a Drosophila melanogaster cDNA encoding a novel 35 kDa protein serine/threonine phosphatase, termed PPV, is presented. PPV is 40-41% identical to Drosophila PP1, 53% identical to Drosophila PP2A and 63% identical to Saccharomyces cerevisiae SIT4. Complementation studies demonstrat...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Catalysis
- Chromosome Mapping
- DNA
- Drosophila melanogaster
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- Phosphoprotein Phosphatases
- Protein Phosphatase 2
- Saccharomyces cerevisiae