Article
Production of interferon-gamma in families with multiple occurrence of schizophrenia.
Psychiatry research - 7 Feb 1997
Arolt V, Weitzsch C, Wilke I, Nolte A, Pinnow M, Rothermundt M, Kirchner H
Abstract excerpt
Dysfunction of T-cell mediated immunity, which is indicated by deficient production of interleukin-2 (IL-2) and elevated levels of the soluble interleukin-2 receptor (sIL-2R), has been consistently demonstrated in schizophrenia. Recent studies on interferon-gamma (IFN-gamma), a cytokine which is also produced by T-helper cells, have indicated a lowered production in acute schizophrenia. It is not known whether...
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