Article
Development of PCR-SSOP for the identification of HLA-A*02 subtypes and determination of HLA-A*02 frequencies within different ethnic populations.
Tissue antigens - 1 Feb 1997
Williams F, Middleton D, Savage D, Gorodezky C, Wilson D W, Fitzgerald J M, Urbaniak S J
Abstract excerpt
A PCR-SSOP typing method, involving a single PCR amplification in conjunction with 19 digoxigenin labelled oligonucleotide probes, has been developed for the identification of 17 known HLA-A*02 alleles. The method has been applied to four populations (Northern Ireland, Singapore Chinese, Shetland Island and Mexican) and percentages of HLA-A*02 alleles determined within each population.
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