Article
Reactive oxygen species as mediators of the transformed phenotype.
International journal of cancer - 4 Mar 1997
Jürgensmeier J M, Panse J, Schäfer R, Bauer G
Abstract excerpt
Reactive oxygen species (ROS) are known to be involved in different pro- and anticarcinogenic mechanisms. However, their influence on the maintenance of the transformed phenotype has not been studied so far. Here we show that the anchorage-independent growth of transformed murine fibroblasts is inhibited by antioxidants and radical scavengers in a concentration-dependent and reversible manner. These agents also...
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